This is a vaccine that protects you against two liver infections: hepatitis A and hepatitis B.
TWINRIX is listed under Health Canada DIN 02230578. The product record and monograph below describe this formulation; the dose schedule comes from the Canadian Immunization Guide.
At a glance
Brand
TWINRIX
DIN
02230578
Vaccine
Hepatitis A (inactivated) + hepatitis B surface antigen
Presentation
720 U + 20 mcg / 1 mL · suspension · intramuscular · 19 years and older
Live vaccine
No
Age and suitability depend on the product, the person and the reason for vaccination. Use the planner for a starting point and confirm with a healthcare professional.
Official sources
Use the DIN to confirm this exact product in Health Canada's Drug Product Database.
A listed product may not be stocked or publicly funded.
Before and after your vaccination
Bring your immunization record if you have one, so earlier doses can be checked.
Tell the healthcare professional about a serious reaction to a previous vaccine or an ingredient, and mention any health conditions or medicines that could affect your vaccination.
After the dose, stay where you can be observed for at least 15 minutes. Tell someone right away if you feel faint or develop symptoms of an allergic reaction.
Keep a record of the vaccine name, date and dose you received.
The details below are adapted from a Pharmasist patient handout linked to the same product monograph. The current Canadian Immunization Guide determines the dose schedules shown later.
What this vaccine helps prevent
This is a vaccine that protects you against two liver infections: hepatitis A and hepatitis B.
It works by helping your body make its own protection (antibodies) against these viruses.
It cannot give you hepatitis A or hepatitis B.
What to mention before a dose
Tell your healthcare professional if you have ever had an allergic reaction to this vaccine, to neomycin, or to any other hepatitis A or hepatitis B vaccine.
Tell them if you have ever fainted after getting a needle.
Tell them if you have a weak immune system, are on medicine that lowers your immune system, or are on dialysis.
Tell them if you have a bleeding problem or bruise easily.
Tell them if you currently have a high fever or a severe illness, since your vaccine may need to be delayed.
How it is given
A healthcare professional gives you this vaccine as a needle into a muscle, usually in your upper arm. Babies usually get it in the outer thigh.
This vaccine is not swallowed and food does not affect it.
Important things to know
Serious allergic reactions are rare but can happen after any vaccine. Your healthcare team will have you stay nearby for about 30 minutes after your shot so they can help quickly if needed.
Fainting can happen before, during, or after a needle. Tell your healthcare professional if you or your child has fainted with a needle before.
If you have a weak immune system, this vaccine may not protect you as fully. Your doctor may check your blood afterward to see if the vaccine worked and if you need extra doses.
Effects you may notice
Pain, redness, or swelling where the needle went in.
Feeling tired.
Headache.
Upset stomach, nausea, vomiting, or diarrhea.
Mild fever.
Feeling generally unwell.
In babies and young children: fussiness, sleepiness, or not wanting to eat.
When to contact a healthcare professional
You have a high fever after vaccination.
The injection site becomes very swollen, painful, or does not improve after a few days.
You develop joint pain, a widespread rash, or hives days or weeks after vaccination.
You feel unusually weak or unwell after your shot.
When to get emergency help
Signs of a severe allergic reaction: swelling of the face, lips, tongue, or throat; hives; an itchy rash; or trouble breathing.
Fainting or passing out.
A seizure.
Sudden weakness or drooping on one side of the face.
Numbness or tingling that does not go away.
Other medicines and vaccines
This vaccine does not interact with food or meal timing.
Tell your healthcare professional about every vaccine, medicine, or natural health product you or your child use, since some vaccines can be given at the same visit and others cannot.
Medicines or conditions that weaken the immune system can make this vaccine work less well.
Key points to remember
Keep a record of every dose you or your child receive, and bring it to every appointment.
Tell every healthcare provider, including your dentist, that you have received this vaccine.
These are Canadian Immunization Guide schedules associated with this DIN. The right schedule depends on age, health, prior doses and reason for vaccination. Public health recommendations may differ from a product monograph's authorized schedule.
Hepatitis A and B (TWINRIX) — adult three-dose series
3 doses
Combined hepatitis A/B vaccine at months 0, 1 and 6 for people 19 years and older.
TWINRIX adult formulation for 19 years of age and older. Dose 2 one month after dose 1, dose 3 six months after dose 1. An accelerated schedule (days 0, 7, 21 and a dose at 12 months) exists for imminent travel; ask your healthcare professional.
General information only. A suggested date is not an appointment or a prescription; a healthcare professional confirms what you need. Clinical rules reviewed on 2026-09-27.