Hepatitis A + B
Hepatitis A and B combined (Twinrix)
TWINRIX · TWINRIX JUNIOR
Three doses over six months. Every product below is a Health Canada authorized vaccine; every schedule comes from the Canadian Immunization Guide.
Products authorized in Canada
Brand names and DINs (Drug Identification Numbers) as Health Canada's Drug Product Database lists them. The product monograph is the manufacturer's full prescribing information approved by Health Canada.
| Product | DIN | What it is | Presentation and age | Official information |
|---|---|---|---|---|
| TWINRIX | 02230578 | Hepatitis A (inactivated) + hepatitis B surface antigen | 720 U + 20 mcg / 1 mL · suspension · intramuscular · 19 years and older | Product guideHealth Canada recordProduct monograph (PDF) |
| TWINRIX JUNIOR | 02237548 | Hepatitis A (inactivated) + hepatitis B surface antigen | 360 U + 10 mcg / 0.5 mL · suspension · intramuscular · 1 to 18 years | Product guideHealth Canada recordProduct monograph (PDF) |
Pregnancy and breastfeeding
Pregnancy
Use if indicated; both components are non-live.
Breastfeeding
Use if indicated.
Source: Immunization in pregnancy and breastfeeding: Canadian Immunization Guide — Chapter updated August 2026. Live vaccines are generally contraindicated in pregnancy; routinely recommended vaccines can be given while breastfeeding unless the chapter says otherwise.
How many doses
The schedules the Canadian Immunization Guide describes for this vaccine. Which one applies depends on age, health and product — use the dose planner to see the dates for your situation.
| Schedule | Doses | Who it is for | Products |
|---|---|---|---|
| Hepatitis A and B (TWINRIX) — adult three-dose series Combined hepatitis A/B vaccine at months 0, 1 and 6 for people 19 years and older. | 3 doses | TWINRIX adult formulation for 19 years of age and older. Dose 2 one month after dose 1, dose 3 six months after dose 1. An accelerated schedule (days 0, 7, 21 and a dose at 12 months) exists for imminent travel; ask the Care365 clinical team. | TWINRIX |
| Hepatitis A and B (TWINRIX Junior) — child three-dose series Combined paediatric hepatitis A/B vaccine at months 0, 1 and 6 for ages 1 to 18 years. | 3 doses | TWINRIX Junior for 1 year to less than 19 years of age. Dose 2 one month after dose 1, dose 3 six months after dose 1. A two-dose adult-formulation schedule for 1 to 15 year olds also exists; ask the Care365 clinical team. | TWINRIX JUNIOR |
Sources
- Hepatitis B vaccines: Canadian Immunization Guide — Chapter revised March 2017 · erratum May 2022
- Health Canada Drug Product Database — product records and monographs
Clinical rules reviewed on 2026-09-27. General information from public Canadian guidance; a personal assessment is needed for treatment decisions. Care365 does not decide whether a vaccine is publicly funded in Ontario.