TWINRIX
Hepatitis A (inactivated) + hepatitis B surface antigen
720 U + 20 mcg / 1 mL · suspension · intramuscular · 19 years and older
Hepatitis A + B
Hepatitis A and B combined (Twinrix)
TWINRIX · TWINRIX JUNIOR
Three doses over six months. Every product below is a Health Canada authorized vaccine; every schedule comes from the Canadian Immunization Guide.
- Products
- 2
- Dose schedules
- 2
- Guidance checked
- 2026-09-27
Authorized products
Brand names and DINs (Drug Identification Numbers) as Health Canada's Drug Product Database lists them. The product monograph is the manufacturer's full prescribing information approved by Health Canada.
TWINRIX JUNIOR
Hepatitis A (inactivated) + hepatitis B surface antigen
360 U + 10 mcg / 0.5 mL · suspension · intramuscular · 1 to 18 years
Before and after vaccination
- Bring your immunization record so earlier doses can be checked.
- Discuss a serious reaction to a previous vaccine, relevant health conditions, medicines and allergies before receiving a dose.
- After vaccination, stay where you can be observed for at least 15 minutes and report feeling faint or signs of an allergic reaction right away.
- Keep the vaccine name, date and dose in your immunization record.
Based on the Canadian Immunization Guide's administration practices and acute reactions guidance.
Pregnancy & breastfeeding
Pregnancy
Use if indicated; both components are non-live.
Breastfeeding
Use if indicated.
Source: Immunization in pregnancy and breastfeeding: Canadian Immunization Guide — Chapter updated August 2026. Live vaccines are generally contraindicated in pregnancy; routinely recommended vaccines can be given while breastfeeding unless the chapter says otherwise.
How many doses
The schedules the Canadian Immunization Guide describes for this vaccine. Which one applies depends on age, health and product — use the dose planner to see the dates for your situation.
Hepatitis A and B (TWINRIX) — adult three-dose series
3 dosesCombined hepatitis A/B vaccine at months 0, 1 and 6 for people 19 years and older.
TWINRIX adult formulation for 19 years of age and older. Dose 2 one month after dose 1, dose 3 six months after dose 1. An accelerated schedule (days 0, 7, 21 and a dose at 12 months) exists for imminent travel; ask your healthcare professional.
ProductsTWINRIX
Hepatitis A and B (TWINRIX Junior) — child three-dose series
3 dosesCombined paediatric hepatitis A/B vaccine at months 0, 1 and 6 for ages 1 to 18 years.
TWINRIX Junior for 1 year to less than 19 years of age. Dose 2 one month after dose 1, dose 3 six months after dose 1. A two-dose adult-formulation schedule for 1 to 15 year olds also exists; ask your healthcare professional.
ProductsTWINRIX JUNIOR
References and product information
- Hepatitis B vaccines: Canadian Immunization Guide — Chapter revised March 2017 · erratum May 2022
- Vaccine administration practices: Canadian Immunization Guide
- Anaphylaxis and other acute reactions: Canadian Immunization Guide
- Health Canada Drug Product Database — product records and monographs
- Pharmasist vaccine reference: TWINRIX JUNIOR
Clinical rules reviewed on 2026-09-27. General information from public Canadian guidance; a personal assessment is needed for treatment decisions. Care365 does not decide whether a vaccine is publicly funded in Ontario.