M-M-R II
Measles, mumps, rubella — live attenuated
0.5 mL · powder for solution · subcutaneous or intramuscular · 12 months and older
MMR & MMRV
MMR and MMRV (measles, mumps, rubella, chickenpox)
M-M-R II · PRIORIX · PRIORIX-TETRA · PROQUAD
Two doses for children and adolescents; one or two for susceptible adults. Every product below is a Health Canada authorized vaccine; every schedule comes from the Canadian Immunization Guide.
- Products
- 4
- Dose schedules
- 4
- Guidance checked
- 2026-09-27
Authorized products
Brand names and DINs (Drug Identification Numbers) as Health Canada's Drug Product Database lists them. The product monograph is the manufacturer's full prescribing information approved by Health Canada.
PRIORIX
Measles, mumps, rubella — live attenuated
0.5 mL · powder for solution · subcutaneous or intramuscular · 12 months and older
PRIORIX-TETRA
Measles, mumps, rubella, varicella — live attenuated
0.5 mL · powder for solution · subcutaneous or intramuscular · 12 months to 12 years
PROQUAD
Measles, mumps, rubella, varicella — live attenuated
0.5 mL · powder for solution · subcutaneous · 12 months to 12 years
Before and after vaccination
- Bring your immunization record so earlier doses can be checked.
- Discuss a serious reaction to a previous vaccine, relevant health conditions, medicines and allergies before receiving a dose.
- After vaccination, stay where you can be observed for at least 15 minutes and report feeling faint or signs of an allergic reaction right away.
- Keep the vaccine name, date and dose in your immunization record.
Based on the Canadian Immunization Guide's administration practices and acute reactions guidance.
Pregnancy & breastfeeding
Pregnancy
Generally contraindicated: MMR and MMRV are live vaccines. Avoid pregnancy for 4 weeks after a dose. Vaccination may be considered during a measles or rubella outbreak.
Breastfeeding
Recommended if not immune.
Source: Immunization in pregnancy and breastfeeding: Canadian Immunization Guide — Chapter updated August 2026. Live vaccines are generally contraindicated in pregnancy; routinely recommended vaccines can be given while breastfeeding unless the chapter says otherwise.
How many doses
The schedules the Canadian Immunization Guide describes for this vaccine. Which one applies depends on age, health and product — use the dose planner to see the dates for your situation.
MMR — children and adolescents (12 months to 17 years), two doses
2 dosesDose 1 at 12 to 15 months and dose 2 at 18 months or later; susceptible adolescents get two doses at least 4 weeks apart.
Two doses of measles-containing vaccine. Children: first dose at 12 to 15 months of age, second at 18 months or any time after, but no later than around school entry. Susceptible adolescents 13 to 17 years: 2 doses of MMR at least 4 weeks apart. Infants 6 to 11 months travelling to high-risk areas may receive an early dose that does not count toward the series.
ProductsM-M-R IIPRIORIX
MMR — adult born in 1970 or later without immunity, one dose
1 doseOne dose for susceptible adults 18 and older born in or after 1970.
Adults born in 1970 or later without documented immunity receive one dose of MMR. Health care workers, travellers, military personnel and post-secondary students should receive two doses instead. Adults born before 1970 are generally presumed immune.
ProductsM-M-R IIPRIORIX
MMR — health care workers, travellers, students, military: two doses
2 dosesTwo doses at least 4 weeks apart for adults at higher exposure risk.
For susceptible adults at higher measles exposure risk (health care workers, travellers, post-secondary students, military): two doses of MMR with a minimum interval of 4 weeks.
ProductsM-M-R IIPRIORIX
MMRV — children, two doses (12 months to 12 years)
2 dosesDose 1 at 12 to 15 months and dose 2 at 18 months or later; not used at 13 years and older.
Combined measles-mumps-rubella-varicella vaccine is authorized for healthy children 12 months to less than 13 years. First dose at 12 to 15 months, second at 18 months or later but before school entry. Minimum interval 4 weeks (3 months recommended for the varicella component). Febrile seizures are slightly more common after a first dose of MMRV than separate MMR and varicella vaccines in 12 to 23 month olds.
ProductsPRIORIX-TETRAPROQUAD
References and product information
- Measles vaccines: Canadian Immunization Guide — Chapter revised April 2015 · partial update June 2025
- Varicella (chickenpox) vaccines: Canadian Immunization Guide — Chapter revised September 2016 · partial update July 2026
- Vaccine administration practices: Canadian Immunization Guide
- Anaphylaxis and other acute reactions: Canadian Immunization Guide
- Health Canada Drug Product Database — product records and monographs
- Pharmasist vaccine reference: M-M-R II
- Pharmasist vaccine reference: PROQUAD
Clinical rules reviewed on 2026-09-27. General information from public Canadian guidance; a personal assessment is needed for treatment decisions. Care365 does not decide whether a vaccine is publicly funded in Ontario.