Hepatitis B
Hepatitis B
ENGERIX-B · RECOMBIVAX HB
Three doses over six months; two for some adolescents. Every product below is a Health Canada authorized vaccine; every schedule comes from the Canadian Immunization Guide.
Products authorized in Canada
Brand names and DINs (Drug Identification Numbers) as Health Canada's Drug Product Database lists them. The product monograph is the manufacturer's full prescribing information approved by Health Canada.
| Product | DIN | What it is | Presentation and age | Official information |
|---|---|---|---|---|
| ENGERIX-B | 02487020 | Hepatitis B surface antigen (recombinant) | 10 mcg / 0.5 mL · suspension · intramuscular · birth to 19 years | Product guideHealth Canada recordProduct monograph (PDF) |
| ENGERIX-B | 02487039 | Hepatitis B surface antigen (recombinant) | 20 mcg / 1 mL · suspension · intramuscular · 20 years and older; 11 to 15 two-dose; dialysis as a double dose | Product guideHealth Canada recordProduct monograph (PDF) |
| RECOMBIVAX HB | 02561476 | Hepatitis B surface antigen (recombinant) | 5 mcg / 0.5 mL · solution · intramuscular · birth to 19 years | Product guideHealth Canada recordProduct monograph (PDF) |
| RECOMBIVAX HB | 02243676 | Hepatitis B surface antigen (recombinant) | 10 mcg / 1 mL · suspension · intramuscular · 20 years and older; 11 to 15 two-dose | Product guideHealth Canada recordProduct monograph (PDF) |
| RECOMBIVAX HB | 02561484 | Hepatitis B surface antigen (recombinant) | 10 mcg / 1 mL · solution · intramuscular · 20 years and older; 11 to 15 two-dose | Product guideHealth Canada recordProduct monograph (PDF) |
| RECOMBIVAX HB | 02245977 | Hepatitis B surface antigen (recombinant), dialysis formulation | 40 mcg / 1 mL · suspension · intramuscular · dialysis and some immunocompromised adults 20 and older | Product guideHealth Canada recordProduct monograph (PDF) |
Pregnancy and breastfeeding
Pregnancy
Recommended for people without immunity who are at high risk of exposure.
Breastfeeding
Use if indicated.
Source: Immunization in pregnancy and breastfeeding: Canadian Immunization Guide — Chapter updated August 2026. Live vaccines are generally contraindicated in pregnancy; routinely recommended vaccines can be given while breastfeeding unless the chapter says otherwise.
How many doses
The schedules the Canadian Immunization Guide describes for this vaccine. Which one applies depends on age, health and product — use the dose planner to see the dates for your situation.
| Schedule | Doses | Who it is for | Products |
|---|---|---|---|
| Hepatitis B — standard three-dose series Standard hepatitis B series at months 0, 1 and 6. | 3 doses | Minimum intervals: 4 weeks between doses 1 and 2, 2 months between doses 2 and 3, and 4 months between doses 1 and 3. The age-appropriate product and dose are chosen by the Care365 clinical team; blood testing after the series is needed for some people. | ENGERIX-B, RECOMBIVAX HB |
| Hepatitis B — adolescents 11 to 15 years, two doses (adult dose) Two adult-strength doses at months 0 and 4 to 6, for adolescents 11 to less than 16 years. | 2 doses | For 11 to less than 16 years of age, the standard adult dose (RECOMBIVAX HB 10 mcg, or ENGERIX-B 20 mcg) may be given as two doses, the second 4 to 6 months after the first, when a three-dose series is unlikely to be completed. | RECOMBIVAX HB, ENGERIX-B |
| Hepatitis B (ENGERIX-B, double dose) — dialysis or weakened immune system, four doses Two 20 mcg injections at each of months 0, 1, 2 and 6. | 4 doses | For adults 20 years and older on dialysis, with chronic renal failure or with some immunocompromising conditions, using ENGERIX-B at double the usual dose (40 mcg) at months 0, 1, 2 and 6. Blood testing after the series is required. | ENGERIX-B |
| Hepatitis B (RECOMBIVAX HB 40 mcg dialysis formulation) — three doses The 40 mcg dialysis formulation at months 0, 1 and 6. | 3 doses | For adults 20 years and older on dialysis, with chronic renal failure or with some immunocompromising conditions: RECOMBIVAX HB dialysis formulation (40 mcg) at months 0, 1 and 6. Blood testing after the series is required. | RECOMBIVAX HB |
Sources
- Hepatitis B vaccines: Canadian Immunization Guide — Chapter revised March 2017 · erratum May 2022
- Health Canada Drug Product Database — product records and monographs
Clinical rules reviewed on 2026-09-27. General information from public Canadian guidance; a personal assessment is needed for treatment decisions. Care365 does not decide whether a vaccine is publicly funded in Ontario.