DUKORAL
Inactivated Vibrio cholerae + recombinant cholera toxin B subunit
Oral suspension · 2 years and older
Cholera
Cholera and travellers’ diarrhea (Dukoral, Vaxchora)
DUKORAL · VAXCHORA
Two oral doses (three for young children), or one live oral dose. Every product below is a Health Canada authorized vaccine; every schedule comes from the Canadian Immunization Guide.
- Products
- 2
- Dose schedules
- 3
- Guidance checked
- 2026-09-27
Authorized products
Brand names and DINs (Drug Identification Numbers) as Health Canada's Drug Product Database lists them. The product monograph is the manufacturer's full prescribing information approved by Health Canada.
VAXCHORA
Vibrio cholerae CVD 103-HgR, live attenuated
Powder for oral suspension · 2 to 64 years
Before and after vaccination
- Bring your immunization record so earlier doses can be checked.
- Discuss a serious reaction to a previous vaccine, relevant health conditions, medicines and allergies before receiving a dose.
- After vaccination, stay where you can be observed for at least 15 minutes and report feeling faint or signs of an allergic reaction right away.
- Keep the vaccine name, date and dose in your immunization record.
Based on the Canadian Immunization Guide's administration practices and acute reactions guidance.
Pregnancy & breastfeeding
Pregnancy
DUKORAL: use if indicated when the risk of severe disease is high. VAXCHORA is a live vaccine and is not given in pregnancy.
Breastfeeding
Use if indicated.
Source: Immunization in pregnancy and breastfeeding: Canadian Immunization Guide — Chapter updated August 2026. Live vaccines are generally contraindicated in pregnancy; routinely recommended vaccines can be given while breastfeeding unless the chapter says otherwise.
How many doses
The schedules the Canadian Immunization Guide describes for this vaccine. Which one applies depends on age, health and product — use the dose planner to see the dates for your situation.
Cholera / travellers’ diarrhea (DUKORAL) — 6 years and older, two oral doses
2 dosesTwo oral doses 1 to 6 weeks apart, finished at least 1 week before travel.
For travellers 6 years and older at high risk of cholera, and 2 years and older for ETEC travellers’ diarrhea: two oral doses 1 to 6 weeks apart. If more than 6 weeks pass between doses, the series restarts. Booster every 2 years for cholera, every 3 months for travellers’ diarrhea while risk continues.
ProductsDUKORAL
Cholera (DUKORAL) — 2 to 5 years, three oral doses
3 dosesThree oral doses each 1 to 6 weeks apart, finished at least 1 week before travel.
Children 2 to less than 6 years at high risk of cholera: three oral doses, each 1 to 6 weeks apart, completed at least 1 week before travel. Booster every 6 months while risk continues. For travellers’ diarrhea alone, two doses are enough.
ProductsDUKORAL
Cholera (VAXCHORA) — one live oral dose
1 doseOne oral dose of live cholera vaccine at least 10 days before travel.
VAXCHORA is authorized by Health Canada for 2 to 64 years of age as a single oral dose against cholera (not travellers’ diarrhea). CATMAT has not yet issued a recommendation; the product monograph governs. Avoid food and drink 1 hour before and after the dose; antibiotics within 14 days may reduce the response.
ProductsVAXCHORA
References and product information
- Cholera and ETEC travellers’ diarrhea vaccine: Canadian Immunization Guide — Chapter revised April 2017
- Vaccine administration practices: Canadian Immunization Guide
- Anaphylaxis and other acute reactions: Canadian Immunization Guide
- Health Canada Drug Product Database — product records and monographs
- Pharmasist vaccine reference: DUKORAL
- Pharmasist vaccine reference: VAXCHORA
Clinical rules reviewed on 2026-09-27. General information from public Canadian guidance; a personal assessment is needed for treatment decisions. Care365 does not decide whether a vaccine is publicly funded in Ontario.