Pneumococcal conjugate — adults 65 and older, one dose
1 doseOne dose of Pneu-C-20 or Pneu-C-21 for all adults 65 years and older.
All adults 65 years and older: one dose of Pneu-C-20 or Pneu-C-21 regardless of earlier pneumococcal vaccination, given at least 1 year after any previous Pneu-C-13, Pneu-C-15 or Pneu-P-23 dose (8 weeks in some circumstances). No further doses are currently recommended.
Pneumococcal conjugate — adults 18 to 64 with risk factors, one dose
1 doseOne dose of Pneu-C-20 or Pneu-C-21 for adults 18 to 64 with a condition that raises the risk of pneumococcal disease.
Adults 18 to 64 with immunocompromising conditions (HIV, asplenia, transplant, cancer, immunosuppressive therapy) or other risk factors for invasive pneumococcal disease (chronic heart, lung, kidney or liver disease, diabetes, alcohol use disorder, cochlear implant, CSF leak): one dose at least 8 weeks after any earlier pneumococcal vaccine. Stem-cell transplant recipients need a three-dose series plus booster instead.