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Vaccine product guide

ABRYSVO

RSV prefusion F protein (subgroups A and B) · RSV

Health Canada DIN 02544040. Check the product and formulation on your record before using a schedule.

Plan doses for this product →
DIN
02544040
Family
RSV
Guidance checked
2026-09-27
← All RSV products

About this vaccine

This vaccine helps protect against serious lung infections caused by respiratory syncytial virus (RSV).

ABRYSVO is listed under Health Canada DIN 02544040. The product record and monograph below describe this formulation; the dose schedule comes from the Canadian Immunization Guide.

At a glance

Brand
ABRYSVO
DIN
02544040
Vaccine
RSV prefusion F protein (subgroups A and B)
Presentation
60 mcg + 60 mcg / 0.5 mL · powder for solution · intramuscular · 18 years and older, and in pregnancy at 32 to 36 weeks
Live vaccine
No

Age and suitability depend on the product, the person and the reason for vaccination. Use the planner for a starting point and confirm with a healthcare professional.

Official sources

Use the DIN to confirm this exact product in Health Canada's Drug Product Database.

A listed product may not be stocked or publicly funded.

Before and after your vaccination

  • Bring your immunization record if you have one, so earlier doses can be checked.
  • Tell the healthcare professional about a serious reaction to a previous vaccine or an ingredient, and mention any health conditions or medicines that could affect your vaccination.
  • After the dose, stay where you can be observed for at least 15 minutes. Tell someone right away if you feel faint or develop symptoms of an allergic reaction.
  • Keep a record of the vaccine name, date and dose you received.

These steps come from the Canadian Immunization Guide's administration practices and acute reactions guidance.

Practical guidance for ABRYSVO

The details below are adapted from a Pharmasist patient handout linked to the same product monograph. The current Canadian Immunization Guide determines the dose schedules shown later.

What this vaccine helps prevent

  • This vaccine helps protect against serious lung infections caused by respiratory syncytial virus (RSV).
  • If you are an older adult, or a younger adult with certain health conditions that raise your risk, it is given to protect you directly against RSV illness.

What to mention before a dose

  • Tell the person giving you the vaccine if you have ever had a severe allergic reaction to this vaccine or any of its ingredients.
  • Tell them if you have a bleeding or clotting problem, since you may bleed more than usual at the injection site.
  • Tell them if your immune system is weakened by a health condition or medicine, since the vaccine may not work as well for you.
  • If you have a fever or feel quite unwell on the day of your appointment, your vaccine may need to be postponed until you feel better; a mild cold is not usually a reason to delay.

How it is given

  • This vaccine is given as a single injection into the muscle of your upper arm by a healthcare professional.

Important things to know

  • Rarely, a nerve condition called Guillain-Barré syndrome, which causes weakness or tingling that can spread through the body, has been reported after this vaccine, mostly in older adults. Tell your healthcare professional right away about any new weakness, numbness, or tingling that starts in the weeks after your vaccine.
  • As with any vaccine given by injection, there is a small chance of a serious allergic reaction, usually within minutes of the injection, so you may be asked to wait at the clinic for a short time afterward.
  • Some people feel faint after getting an injection. Sit or lie down for the vaccination, and let staff know if you feel lightheaded afterward.

Effects you may notice

  • Pain, redness, or swelling where the needle went in.
  • Headache.
  • Muscle aches.
  • Feeling tired.
  • Nausea.
  • Joint pain.
  • Mild fever.

When to contact a healthcare professional

  • If you feel unusually unwell, or your injection site becomes increasingly painful, swollen, or warm in the days after your vaccine.
  • If side effects do not go away after a few days or worry you.

When to get emergency help

  • Signs of a severe allergic reaction, such as swelling of your face, lips, or throat, hives, dizziness, or sudden difficulty breathing, especially within minutes to hours of the vaccine.
  • New muscle weakness, numbness, or tingling that spreads or gets worse over hours to days after vaccination.

Other medicines and vaccines

  • This vaccine can usually be given at the same time as certain other vaccines, such as flu, COVID-19, or whooping cough (Tdap) vaccines, but they should be given as separate injections in different spots on your body, never mixed together in the same needle.
  • Tell your healthcare professional about all vaccines you have had recently or are planning to get.

Key points to remember

  • Bring your vaccination record to your appointment and ask for a copy afterward.
  • Let your healthcare team know about any side effects you experience, especially anything unusual or long-lasting.
  • Even after vaccination, continue to practice good hygiene, since the vaccine reduces the risk and severity of RSV illness but does not guarantee full protection.

The practical points are adapted from the Pharmasist reference for ABRYSVO and its matching product monograph.

Dose schedules

These are Canadian Immunization Guide schedules associated with this DIN. The right schedule depends on age, health, prior doses and reason for vaccination. Public health recommendations may differ from a product monograph's authorized schedule.

RSV — adults 75 and older, one dose

1 dose

One dose of RSV vaccine is recommended for all adults 75 years of age and older.

NACI recommends a single dose of RSV vaccine (AREXVY, ABRYSVO or MRESVIA) for all adults 75 years of age and older. Protection lasts at least 3 years; no repeat dose is currently recommended.

RSV — adults 65 to 74 at increased risk, one dose

1 dose

One dose is recommended for adults 65 to 74 with a condition that raises the risk of severe RSV disease.

NACI recommends a single dose for adults 65 to 74 who are at increased risk: chronic heart or lung disease (including COPD, asthma, cystic fibrosis), diabetes and metabolic disease, moderate or severe immunodeficiency, chronic kidney or liver disease, neurologic or neurodevelopmental conditions, class 3 obesity, or residence in a nursing home. Other adults 65 to 74 may consider it.

RSV — adults 18 to 64 at increased risk, one dose

1 dose

One dose is recommended for the highest-risk adults 18 and older, and may be considered for other adults at increased risk.

NACI recommends a single dose for adults 18 and older who live in a nursing home, have had a lung or stem-cell transplant, are on home oxygen or receive dialysis. Other adults 18 to 64 at increased risk of severe RSV disease may consider a single dose. AREXVY is authorized from 50 years; ABRYSVO and MRESVIA from 18.

RSV (ABRYSVO) in pregnancy — one dose

1 dose

One dose of ABRYSVO during pregnancy to protect the newborn; NACI recommends 28 to 36 weeks, the product is authorized for 32 to 36 weeks.

ABRYSVO only. NACI recommends one dose at 28 to 36 weeks of gestation, before or during the RSV season, at least 2 weeks before birth; Health Canada authorizes 32 to 36 weeks. There is no recommendation for a repeat dose in a later pregnancy; the infant can receive a monoclonal antibody instead.

Check your dose plan →

Pregnancy and breastfeeding

Family guidance on pregnancy: ABRYSVO is recommended at 28 to 36 weeks of gestation, before or during RSV season (Health Canada authorizes 32 to 36 weeks). AREXVY and MRESVIA are not used in pregnancy.

Family guidance on breastfeeding: Not recommended on the basis of breastfeeding alone; the maternal dose protects the infant when given during pregnancy.

This guidance applies to the vaccine family. Confirm this product's details in the monograph and with your clinician. Immunization in pregnancy and breastfeeding: Canadian Immunization Guide — Chapter updated August 2026.

References and product information

General information only. A suggested date is not an appointment or a prescription; a healthcare professional confirms what you need. Clinical rules reviewed on 2026-09-27.

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