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Medication guide

Estradiol (Transdermal Patch)

Relieves menopausal hot flushes and night sweats.

Check the name, strength and form on your own prescription or package.

Brand
Estradot
Form
Menopausal estradiol skin patch
Guidance checked
2026-09-08

About this medication

Relieves menopausal hot flushes and night sweats.

How to use it

Change on the exact brand’s schedule. Apply to approved clean, dry skin away from breasts; rotate sites. A progestogen is generally needed with an intact uterus.

Pregnancy and breastfeeding

Not for pregnancy or breastfeeding. It is not contraception.

Before you use it

Avoid unexplained bleeding, relevant cancers, clotting history and active liver disease.

Possible side effects

Skin irritation, breast tenderness and spotting.

When to get help

Chest symptoms, neurological symptoms or unexpected bleeding need assessment.

Other medicines and products

Enzyme inducers and inhibitors can affect treatment.

Missed doses, storage and accidental exposure

Follow your own product’s missed-dose instructions. If you are unsure, ask the Care365 clinical team before taking an extra dose. Contraceptives, injections and modified-release medicines may need a specific plan.

Keep the original packaging and follow its storage, expiry and disposal instructions. Keep medicines away from children and pets. Ask about refrigeration, after-opening limits and safe sharps disposal when relevant.

For suspected overdose or accidental swallowing, contact poison control or urgent medical care promptly. Call emergency services for breathing difficulty, collapse or a seizure.

References and product information

Sources checked .

Sources checked 2026-09-08. Safety sections are highlights; consult the full product information for complete warnings and instructions.

Check the Canadian Drug Product Database by product name or DIN for current product information.

These practical points come from the Pharmasist patient handout for the same product monograph cited by this guide.

This is a plain-language guide, not the complete monograph. Match the name, strength and form on your package before using product-specific directions.

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