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Medication guide

Doxycycline

Treats selected susceptible bacterial infections; regimens vary by diagnosis.

Check the name, strength and form on your own prescription or package.

Brand
Vibramycin
Form
Standard-release oral antibiotic
Guidance checked
2026-09-08

About this medication

  • Doxycycline is an antibiotic. It treats infections caused by certain bacteria.
  • It is used for chest and airway infections such as pneumonia, bronchitis, and sinus infections.
  • It is used for skin infections, urinary infections, and some sexually transmitted infections.
  • It does not treat colds, flu, or other infections caused by viruses.

Treats selected susceptible bacterial infections; regimens vary by diagnosis.

How to use it

  • Swallow the capsule or tablet whole with a full glass of water.
  • Take doxycycline with food or right after a meal to help prevent an upset stomach.
  • Stay sitting or standing upright for 1 to 2 hours after each dose, and do not lie down right after taking it.
  • Take this medicine exactly as your healthcare professional tells you. The amount and how often you take it will be on your prescription label.
  • Finish the entire course of medicine, even if you feel better, unless your doctor tells you to stop.

If you miss a dose

  • Take the missed dose as soon as you remember.
  • If it is almost time for your next dose, skip the missed dose and continue your regular schedule.
  • Do not take two doses at once to make up for a missed one.

Use the prescribed course. Swallow with ample water and remain upright; do not substitute the 40 mg rosacea formulation.

Pregnancy and breastfeeding

  • Tell your doctor if you are pregnant, trying to become pregnant, or breastfeeding before starting doxycycline.
  • Doxycycline is generally avoided in later pregnancy and while breastfeeding, as it can permanently discolor a baby's developing teeth and affect bone growth.

Pregnancy, breastfeeding and young-child use require specific clinical assessment.

Before you use it

  • Tell your healthcare professional if you have ever had an allergic reaction to doxycycline or any other tetracycline antibiotic.
  • Tell your healthcare professional if you have myasthenia gravis.
  • Tell your healthcare professional if you are taking isotretinoin for acne.
  • Tell your healthcare professional if you are pregnant, trying to become pregnant, or breastfeeding.
  • Tell your healthcare professional if this medicine is for a child under 8 years old, as it is generally not recommended in young children.

Important warnings

  • Doxycycline can irritate your throat or esophagus if it gets stuck there. Always take it with a full glass of water and stay upright for 1 to 2 hours afterward. Do not take it right before bed.
  • Doxycycline can make your skin much more sensitive to sunlight, leading to a bad sunburn. Limit sun exposure, wear protective clothing, and use sunscreen.
  • Rarely, doxycycline has caused increased pressure inside the head, with headache and vision changes. Stop the medicine and get medical help if you have a severe headache along with blurred or double vision.
  • If used during the last part of pregnancy or given to young children, doxycycline can permanently discolor developing teeth and may affect bone growth.
  • Serious allergic reactions and severe skin reactions have happened rarely. Get help right away if you develop a rash, especially with fever, blistering, or swelling.

Avoid tetracycline allergy, myasthenia gravis and concurrent isotretinoin.

Possible side effects

  • Nausea or upset stomach
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Heartburn
  • Sensitivity to sunlight
  • Headache
  • Vaginal yeast infection in women

Nausea, diarrhoea and sun sensitivity; use sun protection.

When to get help

When to get emergency help

  • Chest pain, or pain or difficulty swallowing after taking a dose.
  • Severe headache with blurred vision, double vision, or vision loss.
  • Signs of a severe allergic reaction: swelling of the face, lips, tongue, or throat, hives, or trouble breathing.
  • A severe skin rash, blistering, or peeling skin, especially with fever.
  • Yellowing of the skin or eyes, dark urine, or unusual tiredness.
  • Watery or bloody diarrhea, especially with stomach cramps or fever.
  • Unusual bruising or bleeding.

When to contact a healthcare professional

  • If you get a bad sunburn or skin reaction after sun exposure.
  • If your infection does not seem to be improving.
  • If you develop ongoing diarrhea.
  • If you develop joint pain, muscle pain, or a new rash.

Painful swallowing, severe diarrhoea or headache with visual changes need assessment.

Other medicines and products

  • Take doxycycline with food to reduce stomach upset.
  • Do not take antacids, calcium supplements, or iron supplements at the same time as doxycycline; space them out as far apart as possible if you need both.
  • Tell the Care365 care team about all other medicines you take, especially blood thinners, seizure medicines, and birth control pills, as doxycycline can interact with these.
  • Alcohol may reduce how well doxycycline works, so it is best to avoid or limit it during treatment.

Separate iron, calcium and antacids; review anticoagulants and enzyme-inducing medicines.

Missed doses, storage and accidental exposure

  • Store at room temperature, protected from light.
  • Keep out of reach of children.
  • Return unused or expired medicine to your pharmacy for safe disposal.

Follow your own product’s missed-dose instructions. If you are unsure, ask the Care365 clinical team before taking an extra dose. Contraceptives, injections and modified-release medicines may need a specific plan.

Keep the original packaging and follow its storage, expiry and disposal instructions. Keep medicines away from children and pets. Ask about refrigeration, after-opening limits and safe sharps disposal when relevant.

For suspected overdose or accidental swallowing, contact poison control or urgent medical care promptly. Call emergency services for breathing difficulty, collapse or a seizure.

Key points to remember

  • Always take doxycycline with food and a full glass of water, and stay upright afterward.
  • Protect your skin from the sun while taking this medicine.
  • Do not take antacids or supplements containing calcium, iron, magnesium, or aluminum at the same time as doxycycline.
  • Finish your full course of antibiotics, even if you feel better.

These practical points come from the Pharmasist patient handout for the same product monograph cited by this guide.

References and product information

Sources checked .

Sources checked 2026-09-08. Safety sections are highlights; consult the full product information for complete warnings and instructions.

Check the Canadian Drug Product Database by product name or DIN for current product information.

This is a plain-language guide, not the complete monograph. Match the name, strength and form on your package before using product-specific directions.

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