Brimonidine (Topical)

• This medicine is a gel applied to the face once a day to reduce the ongoing redness of rosacea.

• Wash your hands before applying.
• Apply a small, pea-sized amount to each of five areas of your face: forehead, chin, nose, and each cheek. Spread it smoothly and evenly.
• Avoid your eyes, eyelids, lips, mouth, and the inside of your nose.
• Wash your hands right away after applying.
• You can apply makeup after the gel has been applied.
• Do not apply to broken, irritated skin, open sores, or skin that was recently treated with laser.
• Redness reduction usually starts within about 30 minutes and is strongest around 3 hours; contact your doctor if you see no improvement after 5 days.

If you miss a dose

• Apply it when you remember. If it is almost time for your next dose, skip the missed one -- do not apply extra to make up for it.

• Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, so they can weigh the benefits and risks with you.

• Tell your healthcare professional if you have ever had an allergic reaction to brimonidine or any other skin product.
• Tell them if you have heart or blood vessel problems, low blood pressure, depression, or Raynaud's phenomenon (fingers/toes that turn white or blue in the cold).
• This is not the same medicine as brimonidine eye drops used for glaucoma -- do not substitute one for the other.

Important warnings

• Some people notice their redness or flushing comes back worse than before after using this medicine, especially in the first two weeks. If this happens, stop using it and contact your healthcare professional.
• Keep this medicine away from children. Swallowing even a small amount has caused serious breathing and heart-rate problems in young children requiring hospital care.
• Rarely, this medicine has caused fainting, a very slow heartbeat, or severe allergic swelling.

• Redness, itching, flushing, or a burning feeling on the skin
• Feeling hot or having cold skin
• Dry mouth
• Mild headache or tingling

When to get emergency help

• Swelling of the face, lips, tongue, or throat
• Sudden difficulty breathing
• Widespread hives
• Fainting or a very slow heartbeat

When to contact a healthcare professional

• If your redness or flushing comes back worse than before you started treatment.
• If you develop new redness in areas you weren't treating, such as your neck or chest.
• If skin irritation is severe or does not improve.

• Tell the Care365 care team about all other medicines you take, especially for depression, blood pressure, or sedation, since this medicine can add to their effects.
• Alcohol may add to drowsiness-related effects of this medicine class.

• Store at room temperature (15°C to 30°C). Do not let it freeze.
• Keep out of the reach and sight of children.