Adapalene

• Adapalene is a topical medicine used to treat acne in people 12 years of age and older.

• Wash and dry your skin before applying.
• Apply a thin layer to the affected areas of your face, chest, or back, avoiding your eyes, lips, and the corners of your nose.
• Take this medicine exactly as your healthcare professional tells you. How often you apply it will be on your prescription label.
• It usually takes several weeks of regular use before you notice improvement, and results continue to improve over time, so keep using it as directed even if you don't see changes right away.
• Use only water-based, non-comedogenic makeup, and remove makeup thoroughly before applying this medicine.

If you miss a dose

• If you miss an application, just apply it the next evening as usual.
• Do not apply extra to make up for a missed application.

• Do not use this medicine if you are pregnant or trying to become pregnant.
• Talk to your doctor before using this medicine while breastfeeding, and avoid applying it to your chest area to prevent contact with your baby.

• Tell the Care365 care team if you have eczema or seborrheic dermatitis, since this medicine is not recommended for these conditions.
• Do not use this medicine if you are pregnant or planning to become pregnant.
• Tell your doctor if you are breastfeeding.
• Avoid applying to cuts, sunburned skin, or skin already irritated by other acne products.

Important warnings

• Do not use this medicine during pregnancy. It is related to vitamin A medicines that can cause birth defects.
• If swallowed by accident, this medicine can cause effects similar to taking too much vitamin A; keep it away from children.
• Rare but serious allergic reactions, including swelling of the face and throat, have been reported.

• Dry skin, especially in the first few weeks
• Redness
• Peeling or scaling
• Burning or stinging right after application
• Itching
• Increased sun sensitivity or sunburn
• General skin irritation
• Oily skin
• Small pale patches of skin
• Mild swelling of the face not related to an allergic reaction
• Cold sores may reactivate in some people
• Eye irritation or redness if the product accidentally gets in your eyes
• Your acne may look like it is flaring up when you first start treatment before it gets better

When to get emergency help

• Swelling of your face, lips, tongue, or throat
• Trouble breathing after using this medicine
• Severe skin burning, blistering, or peeling

When to contact a healthcare professional

• Skin irritation that is severe or does not improve
• Signs of an allergic skin reaction, such as hives or significant swelling
• Changes in skin color where you applied the medicine
• Eye pain, redness, or swelling if the medicine gets into your eyes
• If you swallow the medicine by accident

• Avoid using other harsh or drying skin products, such as strong cleansers, alcohol-based products, or other acne treatments containing sulfur, resorcinol, or salicylic acid, at the same time, since this can increase irritation.
• Avoid waxing the treated skin, since it can make irritation worse.
• Limit sun exposure and use sun protection, since your skin will be more sensitive to sunburn while using this medicine.

• Store at room temperature and protect from freezing.
• Keep the container tightly closed and out of the reach of children.