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Medication guide

Acyclovir (Topical)

The Canadian Zovirax reference covers selected genital/cutaneous herpes infections. It does not establish a general cold-sore regimen.

Check the name, strength and form on your own prescription or package.

Brand
Zovirax
Form
5% acyclovir skin cream or ointment
Guidance checked
2026-09-08

About this medication

The Canadian Zovirax reference covers selected genital/cutaneous herpes infections. It does not establish a general cold-sore regimen.

How to use it

Use only for the assessed indication and exact formulation; it does not prevent transmission or eradicate latent virus.

Pregnancy and breastfeeding

Pregnancy, breastfeeding and use under 18 require individual medical review.

Before you use it

Avoid acyclovir/valacyclovir allergy; keep away from eyes and mucous membranes.

Possible side effects

Application-site burning or discomfort.

When to get help

Eye involvement, spreading infection or severe irritation needs assessment.

Other medicines and products

Review other products used on the affected area.

Missed doses, storage and accidental exposure

Follow your own product’s missed-dose instructions. If you are unsure, ask the Care365 clinical team before taking an extra dose. Contraceptives, injections and modified-release medicines may need a specific plan.

Keep the original packaging and follow its storage, expiry and disposal instructions. Keep medicines away from children and pets. Ask about refrigeration, after-opening limits and safe sharps disposal when relevant.

For suspected overdose or accidental swallowing, contact poison control or urgent medical care promptly. Call emergency services for breathing difficulty, collapse or a seizure.

References and product information

Sources checked .

Sources checked 2026-09-08. Safety sections are highlights; consult the full product information for complete warnings and instructions.

Check the Canadian Drug Product Database by product name or DIN for current product information.

The Pharmasist page for Acyclovir gives more background about this medicine. Its linked monograph may describe a different brand, strength or formulation from the one discussed here, so use the exact product and DIN on your package when checking doses and warnings.

A formulation is the form of a medicine, such as a tablet, cream or spray. Products with the same ingredient can have different directions.

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